It is too early to say. The analysis I have seen has been mostly positive, feeling that he made a good speech and hopefully will put the issue to rest.
The candidate who should feel happiest about the speech and the wall to wall coverage should be Mike Huckabee. In part, the speech was in response to the sudden surge of support for the conservative Christian Huckabee. Furthermore, the speech has deflected attention from the sudden rash of reports regarding Wayne Dumond, a convicted rapist who was paroled during Huckabee's time as Arkansas governor. Huckabee's role in the parole is under question. After being released, Dumond raped and killed another woman.
With Huckabee going from a little known candidate to suddenly in the lead in Iowa, the news media has decided to revisit the story. Given the anti-crime emphasis of the GOP, especially the social conservative wing that Huckabee is heavily courting, this could have hurt him badly. But the media has a short attention span, and the issue now is Romney's religion. Huckabee has to hope that the spotlight stays there for a while, then moves off to something else.